The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents
Spared cognitive and behavioral functions prior to epilepsy onset in a rat model of subcortical band heteropia
Deletion of the vesicular monoamine transporter 1 (vmat1/slc18a1) gene affects dopamine signaling
Striatal cholinergic interneurons regulate cognitive and affective dysfunction in partially dopamine‐depleted mice
Inhibition of hematopoietic cell kinase dysregulates microglial function and accelerates early stage Alzheimer's disease-like neuropathology
A two-hit story: Seizures and genetic mutation interaction sets phenotype severity in SCN1A epilepsies
Dorsolateral septum somatostatin interneurons gate mobility to calibrate context-specific behavioral fear responses
Walking activity and dispersal on deltamethrin- and spinosad-treated grains by the maize weevil Sitophilus zeamais
Lasting metabolic effect of a high-fructose diet on global cerebral ischemia
A chinese research group worked on 4 week old mice exposed to Hangzou real airborne for 2 months and were found to display bronchial and alveor damage. CDK5 plays a major role in endothelium cell growth, migration, and molecular transduction.
STAT3 in the dorsal raphe gates behavioural reactivity and regulatesgene networks associated with psychopathology
Posted January 20, 2020.
Endothelium-Derived Semaphorin 3G Regulates Hippocampal Synaptic Structure and Plasticity via Neuropilin-2/PlexinA4
Dopaminergic signalling is necessary, but not sufficient for cued fear memory destabilisation
Rapeseed oil fortified with micronutrients improves cognitive alterations associated with metabolic syndrome
Experience of behavior on mice
Memory traces are believed to be ensembles of cells used to store memories. To visualize memory traces, we created a transgenic line that allows for the comparison between cells activated during encoding and expression of a memory.
Neurocognitive deficits arising from anesthetic exposure have recently been debated, while studies have shown that the phosphorylation of cyclic AMP response element-binding protein (CREB) in the hippocampus is critical for long-term memory.
Null mutations in the gene encoding the major myelin protein of the central nervous system, proteolipid protein 1 (PLP1), cause an X-linked form of spastic paraplegia (SPG2) associated with axonal degeneration. While motor symptoms are the best known manifestations of this condition, its somatosensory disturbances have been described but poorly characterized.
Insulin resistance leads to memory impairment. Cinnamon (CN) improves peripheral insulin resistance but its effects in the brain are not known. Changes in behavior, insulin signaling and Alzheimer-associated mRNA expression in the brain were measured in male Wistar rats