Assess functional vision characteristics in zebrafish
Zebrafish as a model organism for visual behavioral screening has appeared to be a starting point for the development of promising human ophthalmological treatments.
The assessment of zebrafish visual performance should leave no room for guesswork as it is the first step to discovering strategies that zebrafish use to regenerate a damaged retina such as cataracts, diabetic retinopathy, macular degeneration, etc. Reflex visual function can also be assessed to study the relation prey-predator, shoals, conspecific recognition, shape, color cues.
ViewPoint has a wide range of systems to assess such tests : optokinetic response test on larvae and optomotor motor response on adult with our VisioBox system. You can also perform dark/light cycle, optomotor response, optogenetic experiments using our ZebraBox.
Adapted for adults
Although many studies have approached visuomotor capacity and behavioral acuity in zebrafish, the methods were often based on ones used on larval zebrafish that could not be transposed into adult zebrafish in an optimal manner. Our system allows you to conduct pertinent research using factors fully adapted to adult zebrafish.
Rather than simply monitoring eye movement, we also take into account the swimming direction. If the fish responds to a rotating stimulus by swimming clockwise and counterclockwise for equal amounts of time, it is considered that they did not detect the stimulus. On the contrary, if they spend most of their time swimming in the same direction as the stimulus, it is considered that they have detected it.